http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020241748-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_716e9a2606ffd4ba1a2a3917e4a402fd |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate | 2020-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cd271d1255e332f58f0cb575b1cc2f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21440a8c909bf07b34bcdde574537b3f |
publicationDate | 2020-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2020241748-A1 |
titleOfInvention | Method for cell-specifically controlling protein for editing target gene |
abstract | Provided is a method for cell-specifically controlling the editing of a target gene, the method comprising a step for introducing, to a cell, (a) mRNA encoding a first protein that edits a target gene, (b) miRNA-responsive mRNA encoding a second protein that inactivates the first protein, and (c) sgRNA having a guide sequence specifically recognized by the target gene, wherein: the miRNA-responsive mRNA includes (i) a nucleic acid sequence specifically recognized by miRNA, and (ii) a nucleic acid sequence corresponding to a coding region of the second protein; and the miRNA is specifically highly active in the cell. |
priorityDate | 2019-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 236.