Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_936b4cec99b15a91cb86c9b1c6c8ca05 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1264 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
filingDate |
2020-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41ee40712461da06d12f60ae1ba153b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5d9ef71c80949008e23c70c4ef6aecf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc76137981d0466102961f8ca43c5c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9623c40d7e4b6c80aa5b9ccc69e8eb7d |
publicationDate |
2020-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020239737-A1 |
titleOfInvention |
Variants of terminal deoxynucleotidyl transferase and uses thereof. |
abstract |
The present invention relates to variants of Terminal deoxynucleotidyl Transferase (TdT), each of which (i) has an amino acid sequence selected from SEQ ID NO8 10-35, or a functionally equivalent sequence, with at least an amino acid substitution at the position corresponding to residue C302 (with respect to SEQ ID NO: 1) or a functionally equivalent residue in SEQ ID NO8 10-35, respectively, (ii) is able to synthesize a nucleic acid fragment without a template and (iii) is able to incorporate a 3'-O-modified nucleotide into the nucleic acid fragment. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021116270-A1 |
priorityDate |
2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |