Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2020-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b9f8a8b4b878c4f3cbd99c23b34213b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3eb0037562d4ade185aae8777217e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba6aa06b282c9ee9dc274fab1ca887c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c467458056fb3ec748363efb3b82d4c7 |
publicationDate |
2020-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020232115-A1 |
titleOfInvention |
Bifunctional nutlin-lenalidomide derivatives ((4,5-dihydro-1h-imidazole-1-carbonyl)piperazin-1-yl-[linker]-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives) as mdm2 degraders and mdm2-p53 inhibitors for use in cancer therapy |
abstract |
Bifunctional nutlin-lenalidomide derivatives ((4,5-dihydro-lH- imidazole-l-carbonyl) piperazin-l-yl-[linker]-l-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives) of the formula (I),as MDM2 (murine double minute 2) degraders and MDM2-p53 interaction inhibitors for use in inhibiting neoplastic cell growth and cancer therapy |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023049790-A3 |
priorityDate |
2019-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |