| abstract |
Cyclic formyl and cyclic ketone compounds, a preparation method therefor, and a pharmaceutical use. The compound shown in formula (I) better inhibits Zika virus and dengue virus infection and replication, may be used as a drug for treating and preventing diseases caused by Zika virus and dengue virus, and may also become a drug for treating and preventing diseases caused by other flaviviruses, such as yellow fever, West Nile virus infection, Japanese encephalitis caused by Japanese encephalitis virus infection, chikungunya virus infection, hepatitis C, forest encephalitis, AIDS caused by HIV etc., and diseases caused by hand, foot and mouth virus infection etc. The compounds may treat diseases caused by bacterial infections, including inflammatory bowel disease ulcerative colitis and Crohn's disease, diseases caused by Escherichia coli, diseases caused by Staphylococcus aureus etc., and diseases caused by Acinetobacter baumannii. |