| abstract |
The present invention provides a novel apoptosis protein inhibitor or a pharmaceutically acceptable salt thereof, an isomer thereof, a preparation method therefor and a pharmaceutical composition, wherein the definition of each group is as shown in the description. The present invention also provides use of the compound, the pharmaceutically acceptable salt thereof and the isomer thereof in the preparation of a medicament for diseases related to IAP proteins. The compound of the present invention has a better binding affinity to XIAP, cIAP1 and cIAP2 proteins, has a better inhibiting effect on cell growth of MDA-MB-231 breast cancer and PC-3 pancreatic cancer cell lines, and has larger pharmaceutical value and a broad market prospect. |