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publicationDate 2020-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020224504-A1
titleOfInvention Cfdna classification method, apparatus and application
abstract A cfDNA classification method, an apparatus and an application, in the fields of genomics and bioinformatics. The method comprises: calculating copy number variation data of cfDNA in a target sample; calculating a degree of similarity between copy number variation data of target cfDNA and copy number variation data of classification tagged cfDNA; according to said degree of similarity, using an analyzer model to determine a classification of the target cfDNA. The present method can complete diagnosis of as many as three types of genitourinary system tumors at the same time, having relatively high sensitivity and specificity. In particular, sensitivity and specificity for diagnosis and dynamic detection of urothelial cancer is higher than a current clinically used detection method.
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