Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3fcb093a174d5182b5854b704cb09354 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate |
2020-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fbf7ffa85035b8131f7d4432131ffcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fed9e4d5c4252ee636956cae8576e26d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb5483707de015c1d9d0cba4490558b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1aa31f65a1ad8099c04022918003b15 |
publicationDate |
2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020210596-A1 |
titleOfInvention |
Modified prostate apoptosis response-4 (par-4) polypeptide, and methods of production and use |
abstract |
Disclosed herein are polypeptide molecules having Prostate apoptosis response-4 (Par-4) pro-apoptotic activity in cancer cells and enhanced biological half-life, and related methods. Specifically, the disclosure provides a composition comprising Par-4 polypeptide fusion protein, and a method of inducing apoptosis in a cancer cell using the composition, wherein the cancer cell is metastatic. |
priorityDate |
2019-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |