http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020207021-A1

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filingDate 2019-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020207021-A1
titleOfInvention Method for improving calcification of artificial biovalve by way of coating
abstract Disclosed is a method for improving the calcification of an artificial biovalve by way of a coating. The method comprising first placing a pretreated biovalve material into an aldehyde-containing solution for a chemical cross-linking reaction, wherein the concentration of a solute having an aldehyde group in the aldehyde-containing solution is 0.1%-2% (w/w), and the reaction time is 0.5 hours to 2 weeks; then soaking the biovalve material in an amino silicone oil emulsion, wherein the amino silicone oil emulsion has an amino value range between 0.2-0.6 mmol/g and a viscosity between 500-5000 mPa.s, the soaking time is 0.2 hours to 1 week, and the temperature does not exceed 60ÂșC. In the method, by introducing a smooth and soft organic material coating into a biovalve leaflet material, the softness and surface smoothness of the valve leaflet are increased, friction is reduced and the risk of calcification is reduced, thereby extending the service life.
priorityDate 2019-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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