http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020206891-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a00fbe3bc9e40319b2a68dfe059d2cf9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91215 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57488 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-533 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56966 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57407 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate | 2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e6671b22eaca17087d7883dd0c5656a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee99c8a58a73a8ae9983a5b6f0bd99ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85e6e4ca95446786a27962fde0380774 |
| publicationDate | 2020-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2020206891-A1 |
| titleOfInvention | Hexokinase 2 used for detection and test kit for scarce neoplastic cells in body fluid sample |
| abstract | A method using hexokinase 2 to detect scarce neoplastic cells in a body fluid sample, and a test kit. The present method is based on the principle of energy metabolism abnormality of neoplastic cells, using glycolysis marker hexokinase 2 (HK2) as a marker to perform in vitro detection, assisting location and selection of scarce neoplastic cells by means of an addressable micropore array chip or a glass sheet, thereby realizing detection of scarce neoplastic cells having high glycolysis activity in a body fluid sample of a cancer patient. Using the present detection method can detect scarce neoplastic cells having high glycolysis activity in a body fluid sample, and particularly can be used to detect circulating tumor cells of a tumor of mesenchymal origin and circulating tumor cells undergoing epithelial-to-mesenchymal transition of a tumor of epithelial origin, remedying insufficiencies in detecting circulating tumor cells of conventional epithelial marker-based detection, and providing a technical foundation for better clinical application of liquid tumor biopsy. |
| priorityDate | 2019-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.