Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_733f9f206a30eb241a0e7ece400747f1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-15043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-625 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-725 |
filingDate |
2020-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62ff7b5cc9482e70513556b35e30ec49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68539a5265dbe44ec33178415b13cf9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9aafe4337b334c1f9abe73d9c1a66c2a |
publicationDate |
2020-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020193506-A1 |
titleOfInvention |
Chimeric antigen receptors, vectors coding for such receptors and their use in the modification of t cells |
abstract |
The present invention relates to achimeric antigen receptor comprising at least the following components: a) a peptidic structure capable of binding to a ligand; b) an extracellular spacing structure; c) a transmembrane domain; d) none or at least one co-stimulatory domain; and e) at least a TCR-derived activatory domain whereby a second TCR-derived activatory domain comprises the amino acid sequence RKGQRDLY (SEQ ID NO:1),which is capable to bind the lymphocyte specific Src kinase in a phosphorylation independent manner and its use in vectors for transducing T cells which are useful in the treatment of diseases, in particular tumors. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022084491-A1 |
priorityDate |
2019-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |