| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39bf0bb8b07e151d4bcead749d7dd699
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d137f8e7503ba75f6edf7cbdf54e98c7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-575 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0258 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 |
| filingDate |
2020-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1febe6e23edd4684fc18f74c9ea60a30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2728421e644d0ecfb627a67fafd47486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2740a4048d416ff27b2b0062ee92b68e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f0b10742018ced6c19d47e15284c6aa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0552a19e673dcf8a15d115c9d4b782d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c3235277337c212c8f6e10c20df59cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6b1148ccd128b1b0d5e90a2e654c067
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f609b252118bc8aca4f71190eaf1ee0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01587e6b6756adcb511e8c18f8742a4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_568a3c1996363468da8fb5f977c46127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_155414a6273489d95aaf7f512ac4cf8e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1209aff60928a95385d8f80761b9d144
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79353b9de8ce0a25f10d70fd7c63b70 |
| publicationDate |
2020-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020191082-A9 |
| titleOfInvention |
Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof |
| abstract |
A bioconjugate of an E. coli glucosylated O4 antigen polysaccharide covalently linked to a carrier protein and compositions thereof are provided. Also provided are recombinant host cells for producing the bioconjugate, and methods of producing the bioconjugate using the recombinant host cells. The recombinant host cells contain a nucleic acid encoding a glucosyl transferase capable of modifying the E. coli O4 antigen with glucose branching to produce the glucosylated O4 antigen polysaccharide. Bioconjugates of an E. coli glucosylated O4 antigen polysaccharide described herein can be used alone or in combination with one or more additional E. coli O-antigen polysaccharides to induce antibodies against an E. coli glucosylated antigen, and to vaccinate a subject against extra-intestinal pathogenic E. coli (ExPEC). |
| priorityDate |
2019-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |