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publicationDate 2020-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020190905-A1
titleOfInvention Postural orthostatic tachycardia syndrome and crth2
abstract T cell surface marker, CRTH2, is a target for treating Postural Orthostatic Tachycardia Syndrome, a hemodynamic abnormality. Targeting CRTH2 permits control of disease symptoms in POTS, for which no FDA approved treatment is currently available. Cell surface expression on certain T cell subsets characterizes the syndrome. Cell surface expression can be conveniently determined in plasma samples using flow cytometry.
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