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filingDate 2020-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34ab61c0080b328f0b812d07170c2f58
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publicationDate 2020-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020185817-A1
titleOfInvention Method of selecting microorganism isolates on a high-density growth platform
abstract Provided is a method of using a device including a plurality of microscale experimental units. At least one cell and an indicator capable of producing an optical signal are loaded in each of the plurality of experimental units. The device with the loaded contents is incubated at predetermined conditions for a duration of time to grow a plurality of cells. At least one optical property of the contents of each of the plurality of experimental units is measured at multiple time points during the incubation to thereby obtain a time-dependent profile of the optical property for each of the plurality of experimental units. Then the time-dependent profile of the at least one optical property for the plurality of experimental units are analyzed. The result of the analysis can be used to determine whether the loaded contents include any biological entity of interest.
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