http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020177455-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31e34094cae9c37769c7069066e07652 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-02001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y402-99 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-26 |
filingDate | 2019-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1cbf3d5855113e7a7c9bb523bee14b6 |
publicationDate | 2020-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-2020177455-A1 |
titleOfInvention | Small-molecule hyaluronic acid or salt thereof, and preparation method therefor |
abstract | Provided are a small-molecule hyaluronic acid or a salt thereof, and a preparation method therefor. Lactobacillus plantarum having culture collection number CGMCC NO. 16836 is fermented to produce a hyaluronidase solution. The hyaluronidase solution enzymatically hydrolyzes a hyaluronic acid or a salt thereof having a molecular weight of between 500 kDa and 700 kDA, and an obtained small-molecule hyaluronic acid or a salt thereof has a molecular weight of between 1 kDa and 60 kDa. The small-molecule hyaluronic acid enzymatic hydrolysate is subjected to enzyme inactivation, activated carbon impurity absorption, micropore membrane filtration, and low-temperature spray drying to obtain a small-molecule hyaluronic acid or a salt thereof. The resulting product features high safety, excellent transdermal absorbability, ensures the integrity and bioactivity of the molecular structure, and has broader applications. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112189765-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114250212-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112189765-B |
priorityDate | 2019-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.