Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43b5898e2124ad90515f966f9eddfe44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a5b5e0c0db30e37fa7679f20fc103af1 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate |
2020-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff620de8c95f37baa7fafb1b22b13fa5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42f6bd2c025f67e9f5e674b155f11537 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e087b238a31152b89b0143811c9d3540 |
publicationDate |
2020-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020176983-A1 |
titleOfInvention |
Amide-based proteolysis modulators of b-rapidly accelerated fibrosarcoma (braf) and associated uses |
abstract |
The present application relates to novel compounds of Formula (I) containing a E3 ubiquitin ligase binding moiety linked to a Raf protein kinase binding moiety. The present application also includes methods and uses of the compounds, for example, for inhibiting and/or degrading V600E mutant B-Raf. I |
priorityDate |
2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |