| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc2b03342511abc88f60c63f2acd96d0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0065 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6841 |
| filingDate |
2020-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f87234e121233e9b77b1a00afd31725c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78118034ec1f82b8b13c1fe1e125612a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6eba7563ff924cab6b01657166e47951
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf7f7d08f7ba8772cfa1f6bfb28ebbfa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2568dfac460a46a445749958412666ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6277231ebadc7e571f6b6d52529eda43 |
| publicationDate |
2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020176534-A1 |
| titleOfInvention |
Multiplexed signal amplification methods using enzymatic based chemical deposition |
| abstract |
Provided herein, among other things, is a method for analyzing a sample. In some embodiments, the method makes use of a plurality of binding agents that are each linked to a different oligonucleotide, as well as a corresponding plurality of peroxidase-linked oligonucleotides, wherein each of the peroxidase-linked oligonucleotides specifically hybridizes with only one of the binding agent-linked oligonucleotides. In some embodiments the method may comprise labeling the sample with the plurality of binding agents en masse, and then staining the sample by hybridizing a single peroxidase-linked oligonucleotide with the sample to produce complexes that comprise the peroxidase and then treating the sample with at least one tyramide-label conjugate. The peroxidase in the complexes activates the conjugate and causes covalent binding of the label to the sample near the complexes. Reagents and kits for performing the method are also provided. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023154452-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112083467-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112083467-B |
| priorityDate |
2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |