http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020174077-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4754c9dee40486a7c206a85a4658270 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9499bfaa0f7c82a0a4bc86f34406d477 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B40-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B40-20 |
| filingDate | 2020-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60c6e2daa6cd24408ba0a3178ad862c5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b04eb7ac93aa502b36e34eb7a3520ee9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b10254a878cfb6cea9e8a2dd2b71076 |
| publicationDate | 2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2020174077-A1 |
| titleOfInvention | Method for determining responsiveness to an epitope |
| abstract | Method (100) for determining an immune responsiveness to a query epitope (126) comprising: receiving sequence data (122) comprising TCR sequences of at least a part of a TCR repertoire of a subject; selecting a predictive model (160) generated or trained using a dataset comprising TCR sequences known to bind specifically to a model epitope, said predictive model selected according to a sequence match between the model epitope and query epitope; querying (130) the selected predictive model (160) with the sequence data (122); determining (140) from outputs of the selected predictive model (160) a Responsiveness Score indicative of the immune responsiveness. The immune responsiveness can be used to predict and optimal vaccine composition and/or evaluate efficacy of a vaccine in a subject or population. |
| priorityDate | 2019-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.