| abstract |
Provided is a Rotigotine stabilization method for a Rotigotine-containing patch provided with a support layer and an adhesive layer, the adhesive layer containing Rotigotine and/or a pharmaceutically acceptable salt thereof, and a styrene-based thermoplastic elastomer, wherein the method stabilizes the Rotigotine and/or a pharmaceutically acceptable salt thereof. Crosslinked polyvinyl pyrrolidone is further contained in the adhesive layer such that the content of the crosslinked polyvinyl pyrrolidone in the adhesive layer is 3-25 mass%. |