| abstract |
The invention relates to a compound of formula (I) R 1 - W m -X n -AA i - AA 2 -AA 3 -AA 4 -AA 5 -AA 6 - Y p -Z q -R a , a stereoisomer and/or cosmetically acceptable salt thereof wherein: AA 1 is Asp, Gly, Asn, Gln, Ala or no amino acid; AA 2 is Val, Ile, Leu or Ala; AA 3 is Tyr, Phe, Trp, Lys, Arg or His; AA 4 is Lys, Arg, His, Pro or Val; AA 5 is Asn, Asp, Gln or no amino acid; AA 6 is Thr, Ala, Ser or no amino acid. The compounds are useful for the treatment and/or prevention of the symptoms of skin aging and, in particular, for the treatment and/or prevention of skin wrinkles, the treatment and/or prevention of a sagging appearance of the skin, and/or the reduction and/or prevention of facial asymmetry. |