abstract |
Disclosed are a pharmaceutical compound and a preparation method therefor and a use thereof. The pharmaceutical compound comprises an active ingredient and a carrier; the carrier is albumin, the active ingredient is loaded on the carrier, and the active ingredient is a platinum-based drug. Compared with free platinum-based drugs, the pharmaceutical compound can significantly extend the in vivo half-life period of the platinum-based drugs, improve the in vivo tissue distribution of the platinum-based drug, improve the tissue selectivity of the platinum-based drug, reduce systemic toxicity and the damage of the platinum-based drug to normal tissues, and improve the therapeutic effect. |