Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_493081e8ebdea47a7436ac10dbf6361c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8139 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-22017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
2019-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd16a0ceee6086b1c9e3afc4437f1bc9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94660c42160053d4ec9aad9ebcee9ad0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0043b395455d86955a7b7eafd89e4cad |
publicationDate |
2020-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020147176-A1 |
titleOfInvention |
Polypeptide having effect of inhibiting proliferation of leukemia cells |
abstract |
Disclosed is a polypeptide having an effect of inhibiting the proliferation of leukemia cells, and the present invention specifically relates to the use of a polypeptide in a drug for treating leukemia. The polypeptide consists of 37 amino acids, with the amino acid sequence thereof being Lys-Glu-Ser-Met-Asp-Ala-Asn-Lys-Pro-Thr-Lys-Asn-Leu-Pro-Leu-Lys-Lys-Ile-Pro-Cys-Lys-Thr-Ser-Ala-Pro-Ser-Gln-Ser-Phe-Phe-Ala-Arg-Asp-Asn-Thr-Ala-Asn, and the N-terminus of the polypeptide being connected with myristic acid. The polypeptide prepared by the present invention can enter the leukemia cells by connecting with the myristic acid, thereby achieving the effect of inhibiting the proliferation of the leukemia cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114605499-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114605499-B |
priorityDate |
2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |