abstract |
Described herein are combination pharmaceutical compositions including a combination of hydrophilic and hydrophobic therapeutic agents ( i.e. , drugs) that are assembled together with excipients under specific conditions, forming a homogeneous pharmaceutical powder with unified repetitive multi-drug motif (MDM) structure. Unlike currently available drug combination powders, which are amorphous, the combination pharmaceutical compositions ( e.g. , combination therapeutic agent powders) of the present disclosure have long range order, in the form of repetitive multi-drug and unified motifs |