| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23624c07555fe0d130491921125ee09c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
| filingDate |
2019-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62d05940b78b53c41e7945a3d644ca2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac3dfa259408bea7c5d7888a08c48296
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb22a6f58ba7984c18859e661329165a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c074328e68c833a1a34cc18f358c918
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71d98731f20a9dc0d85d1c77b23f3b71 |
| publicationDate |
2020-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020138952-A1 |
| titleOfInvention |
Composition for converting insulin precursor into insulin enzyme and method for converting insulin precursor into insulin by using same |
| abstract |
The present invention relates to: a composition for an enzyme conversion reaction for converting proinsulin or a proinsulin analogue into insulin or an insulin analogue, the composition containing one or more selected from the group consisting of calcium chloride, glycine and proline, and trypsin and/or carboxypeptidase B; and a method for converting proinsulin or a proinsulin analogue into insulin or an insulin analogue by using the composition. The present invention increases the structural stability of an insulin protein and the stability of the enzyme at the same time so as to significantly improve the enzyme conversion yield and the purity of insulin, thereby being useful in insulin production processes. |
| priorityDate |
2018-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |