| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a43ef275ae6f6fafc66975041eb60aa7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-06013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 |
| filingDate |
2019-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac847cd14278634906a55fca795d3b5d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c844d4f1a940c56ec0b7f412fb15001f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c53497088ee66e68c8cf19b835bea03a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_310fd7428376eca0ee340775adbef33f |
| publicationDate |
2020-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020132452-A1 |
| titleOfInvention |
Purification of iduronate-2-sulfatase immunoglobulin fusion protein |
| abstract |
The present invention relates to an improved composition comprising purified fusion protein including an immunoglobulin and an iduronate-2-sulfatase (12S). In some embodiments, the fusion protein comprises at least about 60% conversion of the cysteine residue corresponding to Cys59 of SEQ ID NO:1 [wild-type human 12S] to C α-formy lgly cine (FGly), wherein the purified fusion protein is characterized with between 1% and 10% 2- mannose-6-phosphate (2-M6P) peak area on glycan map. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114316072-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022174114-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023068740-A1 |
| priorityDate |
2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |