http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020132349-A2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
filingDate 2019-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_620d1905c624a68c87cc0161b5e9854b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58fa328f3a6a26d15afc7f841e000825
publicationDate 2020-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020132349-A2
titleOfInvention Optimizing detection of transplant injury by donor-derived cell-free dna
abstract Herein are novel methods of detecting subacute and active rejection in graft recipients, including kidney recipients by the measurement of donor-derived cell-free DNA. By the methods, active rejection processes encompassing T -cell mediated rejection may be detected. Also provided herein are novel threshold values for the determination of active rejection that enable higher sensitivity and specificity than prior methods. Additionally, by donor-derived cell-free DNA, subacute rejection processes can be detected, including borderline rejection and other graft injuries.
priorityDate 2018-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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