| abstract |
The present invention relates to novel compounds, compositions containing same and methods for inhibiting STAT3 and/or STAT5 activity or for the treatment of a cell proliferative disorder such as a cancer using a compound of formula (I) or a pharmaceutically acceptable salt, solvate or hydrate thereof, wherein R and R 1 , different, are selected from the group consisting of -H, (Ia), (Ib) and (Ic), wherein when one of R and R 1 is a –H, the other of R and R 1 is a cyclopentyl moiety, R 2 is a benzyl substituted with 1-5 halogens, preferably –Cl, F or –Br, and R 3 is selected from the group consisting of -H or –OH.=. |