http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020117849-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-4055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-7233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2019-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c452670374ef82f3e58ebd2485c43ac9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79cc1fee7bdffcb44baea48c366e1274 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d0e63a5115d157b837a29978117486ea |
| publicationDate | 2020-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2020117849-A1 |
| titleOfInvention | Methods of analysis using in-sample calibration curve by multiple isotopologue reaction monitoring |
| abstract | This disclosure provides several methods in LC-MS/MS analysis: (1) a method of LC-MS/MS analysis technique to determine the analyte concentration of a sample wherein an In-Sample Calibration Curve (ISCC) is used instead of an external calibration curve through monitoring of multiple isotopologue transitions of an added stable isotopically labeled (SIL) analyte in each sample via MS/MS in multiple isotopologue reaction monitoring (MIRM) mode; (2) a method of LC-MS/MS analysis to determine the analyte concentration of a sample wherein a One-Sample Multipoint External Calibration Curve (OSMECC) is used instead of a multisample external calibration curve; and (3) a method of LC-MS/MS analysis to determine the analyte concentration of a sample with an analyte concentration beyond the assay's ULOQ wherein isotope sample dilution is used instead of diluting sample physically during sample preparation based on calculating the isotopic abundance of the MIRM channel monitored. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112326851-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11232936-B2 |
| priorityDate | 2018-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 276.