| abstract |
Provided are a histone acetylase p300 inhibitor and a use thereof, belonging to the field of medicinal chemistry technology. A compound represented by formula (I), or a stereochemical isomer thereof, or a solvate thereof, or a pharmaceutically acceptable salt thereof, can inhibit the activity of histone acetylase p300 and inhibit the proliferation activity of a variety of tumor cells. <img file="577633dest_path_image001.jpg" he="80.79" img-content="drawing" img-format="jpg" inline="yes" orientation="portrait" wi="88.19"/> |