| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_846aa2210a803790c76f15d902f790bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7bae7cf399c53b51787e575edaf8b820 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0459
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B59-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate |
2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b13f191e9505b987924896ad8338873a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_290ba31f38eace2392c4f78cca67d788
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad96a080ab8ac863a5674ef0e898392e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8837f69507ef55133ed02fb8b43ae3ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0387e71077b8ac0d789f0237122aabdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_861f721d2aa81489888d3dfe579fd9e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_182c634414b1815d08724c83274c9b78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56fa4ce5fe7bc7136c3b151a679c1feb |
| publicationDate |
2020-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020103392-A1 |
| titleOfInvention |
18f-pet/ct tracer comprising 7-deazaadenine base as parent nucleus and preparation method therefor |
| abstract |
Disclosed in the present invention are an 18F-PET/CT tracer comprising 7-deazaadenine base as a parent nucleus and a preparation method therefor. Disclosed in the present invention are a compound represented by formula I or a pharmaceutically acceptable salt thereof, wherein R1 and R2 are each independently selected from H or C1-C5 alkyl; and X is independently selected from 11C, 18F, 15O or 13N. Also disclosed in the present invention are a preparation method for and use of the compound represented by formula I. The present invention successfully prepares an 18F-PET/CT tracer comprising 7-deazaadenine base as a parent nucleus: 18F-HX tracer. Experimental results show that the 18F-HX tracer prepared in the present invention can be taken up stably in tumors, which is three times higher than that in muscle tissue. Thus, the 18F-PET/CT tracer of the present invention is desirably applied to PET/CT imaging, and changes the situation wherein there is a lack of tracers for lung cancer. (I) |
| priorityDate |
2018-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |