http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020101032-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1133 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-54 |
| filingDate | 2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ccbd9c4a9284f5b28c8dc4d956a2db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b538a399abb67f3cdf65f8a713ff8d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd771330928a9e11dea80c7b76b543d5 |
| publicationDate | 2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-2020101032-A1 |
| titleOfInvention | Method for producing cyclized peptide having intramolecular s-s bond |
| abstract | The present invention provides a method for producing a cyclized peptide having a structure crosslinked by one or more intramolecular S-S bonds as indicated below. A method for producing a cyclized peptide, the method including: (1-A) a step in which, in a linear peptide ("fully protected peptide") that has two or more SH groups as functional groups on the peptide, the linear peptide being such that all of the SH groups are protected, the N-end amino group may be protected, and the C-end carboxy group and all of the other functional groups on the peptide are protected, all of the functional groups other than the protected SH groups of the peptide are deprotected; (1-B) a step in which, in a linear peptide having two or more SH groups as functional groups on the peptide, all of the SH groups are protected by forming temporary S-S bonds; and (2) a step in which a peptide ("S protected peptide") that has two or more SH groups as functional groups on the peptide, that is such that all of the SH groups are protected by formation of temporary S-S bonds and all of the other functional groups of the peptide are deprotected, and that is obtained in step (1-A) and step (1-B) is subjected to a folding step under redox conditions to reform the S-S bonds within the peptide molecule, whereby a cyclized peptide is obtained. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022097500-A1 |
| priorityDate | 2018-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 273.