Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3045fc9dfbc8ee2939b1a99edbd7268c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate |
2019-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15d0ab70c89f07ebc69bd149c39b448d |
publicationDate |
2020-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020099929-A1 |
titleOfInvention |
A crystalline spirocyclic compound inhibitor of tryptophan hydroxylase 1 (tph1) for treating diseases or disorders associated with peripheral serotonin |
abstract |
There is a crystalline compound of (S)-ethyl 8-(2-amino-6-((R)-1-(5-chloro-[1,1'- biphenyl]-2-yl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylate that exhibits an XRPD pattern having a characteristic peak at 19.05 ± 0.20 (°2Θ). There is also a pharmaceutical composition containing the compound. There is also a dosage form containing the crystalline compound and a pharmaceutically acceptable excipient. There is also a method for crystallizing/recrystallizing the compound. There is also a method for treating or preventing a disease with the compound. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023062595-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11413287-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11607413-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021152398-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11576915-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020157577-A1 |
priorityDate |
2018-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |