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filingDate 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_486b76f87ea69a607f6ef260f7bf7ae3
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publicationDate 2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020097070-A1
titleOfInvention Mutagenized il13 and methods of use
abstract Disclosed is a conjugated mutagenized IL13, comprising a mutagenized IL13 (mIL13) conjugated to a conjugatable agent. Also disclosed is an extracellular vesicle complex, comprising an extracellular vesicle complexed with a conjugated mutagenized IL13. Also disclosed are methods of detecting an IL13-specific receptor in a sample, comprising contacting a portion of a sample with a conjugated mutagenized IL13 (mIL13) or an extracellular vesicle complex. Also disclosed are methods for diagnosing cancer in a subject, comprising administering a conjugated mutagenized IL13 or an extracellular complex, and diagnosing the subject with cancer when a level of conjugated mIL13 binding to a target of the subject is detected. Also disclosed are kits comprising a conjugated mutagenized IL 13 or an extracellular complex.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023086896-A1
priorityDate 2018-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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