Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5137d258248f7d51a126917b4cd77e97 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y104-03016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-02019 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y104-03016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y205-01072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-02019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0022 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00 |
filingDate |
2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1fd71b2a032ba1555108cac6ac72a51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b991a7c98ec8886396de012e483a5ab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5d8decf72ca1946f80442dd14275121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60d4c6529c3c196a1af27a3c703bdcea |
publicationDate |
2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020094828-A1 |
titleOfInvention |
Microbial hosts engineered for increased tolerance to temperature shifts |
abstract |
The present invention relates to microbial host cells that have been engineered for increased tolerance to temperature shifts, for increased performance at temperatures different from the microorganism's optimal temperature and/or for changing at least one of the microorganism's cardinal temperatures by replacing an endogenous NAD+ biosynthesis gene by a heterologous gene encoding a corresponding enzyme with another temperature profile and/or from a microorganism with a different optimum growth temperature.The invention further relates to processes wherein the engineered microbial host cells are used for producing a fermentation product,and to the use nucleotide sequences encoding NAD+ biosynthesis gene for changing at least one of a microorganism's cardinal temperatures and/or for improving a microorganism's tolerance to temperature shifts. |
priorityDate |
2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |