| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90d863c6ac1f6b17c8da3f59358e97ed |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0621
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0619
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-062
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0622
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
| filingDate |
2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64a7e68c6b9db524e8cd11c867b017de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a4859edd059686502483b5cb6e9c97d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e6fdb3de41a939b1a3fb312a705c2cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb6b297e029a63c3ed4c96dd8727ab00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7863c27cef7ae24fda9247406a03575 |
| publicationDate |
2020-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020093147-A1 |
| titleOfInvention |
Recombinant nervous system cells and methods to generate them |
| abstract |
The instant disclosure provides a recombinant nervous system cell comprising nucleic acid encoding IKAROS Family Zinc Finger 4 (Ikzf4) and/or IKAROS Family Zinc Finger 1 (Ikzf1)); a vector comprising a glial specific promotor operably-linked to a nucleic acid molecule encoding IKAROS Family Zinc Finger 1 (Ikzf1) and/or a nucleic acid molecule encoding IKAROS Family Zinc Finger 4 (Ikzf4); and methods of producing a recombinant cone photoreceptor, comprising: (A) (a) introducing a nucleic acid molecule encoding IKAROS Family Zinc Finger 1 (Ikzf1) in a Müller glia cell; and (b) introducing a nucleic acid molecule encoding IKAROS Family Zinc Finger 4 (Ikzf4) in the Müller glia cell; or (B) introducing a nucleic acid molecule encoding Ikzf4 in a retinal neuroepithelial cell; whereby the retinal neuroepithelial cell or the Müller glia is reprogrammed into a recombinant cone photoreceptor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114350664-A |
| priorityDate |
2018-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |