| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0de2fbe5faca1f3e33ff1cd880df2873
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c06d728f2a623a6264c98cd431958946 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8213
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01H6-4636 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
| filingDate |
2019-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fdb92b4822f06a656483143e5227fb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b0d1f8110e8fcaa6f97c462aa665393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d626061501a583671d13fe77a7bc6e28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f21451d4a4fe64570470b1a7567f22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bdaa4e6075cddb78a85fc0d64e30fd95
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f6b5e911737cc9d0bf225250f968267 |
| publicationDate |
2020-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020089489-A1 |
| titleOfInvention |
Targeted mutagenesis using base editors |
| abstract |
The present invention relates to novel methods for discovering traits and generating cellular systems having improved phenotypes. In particular, the present invention provides methods for the development of plants having agronomically optimized phenotypes by using targeted mutagenesis with few or no off-target effects. Targeted mutagenesis is achieved by the introduction of a base editor complex or of a STEME complex comprising an array of guide RNAs targeting a nucleic acid sequence of interest. The present invention also relates to cellular systems obtained by the methods described herein and to the use of a base editor complex or the STEME complex comprising an array of guide RNAs for generating a cellular system having an agronomically important phenotype and for identification of an agronomically important phenotype. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023050158-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113215190-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113215190-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021155109-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111549053-A |
| priorityDate |
2018-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |