Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db8acd71f5994544bda6df3f27a3f51e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_874097335aa3a75db3a501e54436badf |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00d607a386d697439a77da7a8a213b3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8cb185fda344c7e9f4639541c64d85c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_231d844d268b7b6d031dce0d3b243a77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e2354caa1755f9a72efc21954cbcf05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55877c53ac132582cfd3be9dace74e6d |
publicationDate |
2020-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020087178-A1 |
titleOfInvention |
Genetically encoded fluorescent indicators under optogenetic control and uses thereof |
abstract |
Disclosed are methods and compositions for real-time monitoring cellular calcium ion dynamics by red-shifted genetically encoded indicators under optogenetic control, in which millisecond-timescale of temporal control of optical activation or inactivation and signal recording can be achieved. The methods include artifact-free functional imaging in conjunction with optogenetic tools for studying cellular physiology, signal transduction and neuronal activity. Thus, all-optical and non-invasive approaches for drug screening, toxicity testing and assessment of cell functions may be provided. |
priorityDate |
2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |