| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1567ae0f1a4843ae7bbef88fa8e1c534 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-50 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0066
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-68 |
| filingDate |
2019-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2679ff951bd683ce1e5c8db0b0f68c29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c18fdc798c880a7c2645a5b3cae2ed16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bea909ac7e2f068027c85986de6a1399
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9a552d174b0476e646d00299be91137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f34202d6da3ce758aea670556f52f200 |
| publicationDate |
2020-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020074642-A1 |
| titleOfInvention |
Plasmid containing a sequence encoding an mrna with a segmented poly(a) tail |
| abstract |
The present disclosure provides a DNA plasmid comprising a sequence which encodes an mRNA molecule and a modified poly(A) tail, wherein the part of the sequence that encodes the modified poly(A) tail is characterized in that it consists of at least two A elements each defined as a nucleotide sequence consisting of 55 to 65 T nucleotides and at least one S element each S element consisting of one nucleotide that is not a T nucleotide, or 2 to 10 nucleotides, preferably 6 nucleotides, wherein each of the two terminal nucleotides is not a T nucleotide, wherein the number of A elements is one more than the number of S elements, and wherein any two A elements are separated by one S element; said DNA plasmid exhibiting a reduced recombination during amplification in a bacterial host cell compared to the same DNA plasmid without said at least one S element, |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11345920-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11286492-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11761009-B2 |
| priorityDate |
2018-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |