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filingDate 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19e3298577f740ec267a798d5665e2ad
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publicationDate 2020-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020069987-A1
titleOfInvention Spherical beads for use in producing pharmaceutically active pellets
abstract In order to provide improved spherical beads that may be used in producing pharmaceutically active pellets by depositing a pharmaceutically active agent on the surface of said spherical beads the present invention provides spherical beads consisting of a pharmaceutically acceptable carrier material, said carrier material consisting of a) at least 60 wt.% of phosphoric acid calcium salt and b) up to 40 wt.% of organic material, wherein ≥ 90 wt % of the spherical beads have a particle size in the range of from 90 µm to 200 µm, and wherein the spherical beads have - a bulk density of at least or more than 1000 g/l, - a specific surface area of at most or less than 10 m2/g and - a hardness of at least or more than 600 g/mm2. Further, the invention is directed to a method for producing such spherical beads and to pharmaceutically active pellets being prepared by depositing a pharmaceutically active agent on the surface of the spherical beads.
priorityDate 2018-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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