http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020063892-A1

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publicationDate 2020-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020063892-A1
titleOfInvention Industrial method for simultaneously preparing stevia rebaudiana chlorogenic acid and stevioside
abstract Disclosed is an industrial method for simultaneously preparing stevia rebaudiana chlorogenic acid and stevioside. The industrial method includes carrying out alcohol extraction on stevia rebaudiana which is used as a raw material, and then adjusting the feed liquid state to allow chlorogenic acid to be in a free molecular state; carrying out extraction separation by a water-insoluble moderate-polarity organic solvent; enriching the stevia rebaudiana chlorogenic acid in an organic layer; and enriching the stevioside in a water layer. Compared with a traditional water extraction process, the method has the advantages that chlorogenic acid ingredient in the stevia rebaudiana can be prevented from being hydrolyzed, such that the contents and effects of effective ingredients in stevia rebaudiana chlorogenic acid products can be guaranteed; effective separation can be carried out on the premise that the quality and the production efficiency of stevioside products are unaffected, the production efficiency can be improved, and the proportion of isochlorogenic acid in the resulting products is close to the proportion of isochlorogenic acid in the raw material; production water consumption can be reduced, and discharge of sewage and flocculation residues can be decreased; and accordingly, the method is a green production process with high benefits.
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