abstract |
Provided are an immune composition, a preparation method therefor, and a use thereof. In the present invention, a prokaryotic expression system or a recombinant adenovirus system is used to highly efficiently express VZV envelope gE glycoprotein and the flagellin fusion protein thereof. The produced recombinant gE protein, gE flagellin fusion protein, and recombinant adenovirus vector, or compositions thereof is used to immunize a mouse so as to promote the body to generate gE and VZV specific antibody titer, as well as gE and VZV specific cell immunity. |