| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61H2230-255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61H2230-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61H2230-085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61H2201-5094 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-4064
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61H31-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-39044
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-14553
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-369 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-0476
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00 |
| filingDate |
2019-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3d0afd4b5a3d2969a13556969753a7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d45ee0ea992bc63cc0c4b12bb9f2a8e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96a0dff4e19098b5fdead15fb1a93205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed7f00dcb1c796870261f32d36098d06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_074666c8734170ad0318f40f3b3dc20b |
| publicationDate |
2020-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020061576-A1 |
| titleOfInvention |
Spreading depolarization and repolarization as biomarkers of neurological recovery after cardiac arrest |
| abstract |
Electrophysiologic biomarkers for prognostication of neurological outcome are described herein. An inverse correlation was found between timing of a cortical spreading depolarization (SD) wave and neurological outcome as tested at 24 hours post-CPR. Additionally, a mirror image of this SD was identified as a "repolarization (RP) wave." Quantifying features of SD and RP during cardiac arrest and cardiopulmonary resuscitation (CPR) provide important metrics for diagnosis and prognosis of neurological injury from hypoxia-ischemia and can serve as an early prognostication tool for predicting outcome at subsequent days after successful CPR. This discovery may also allow for novel therapeutic interventions to improve neurological recovery after hypoxia-ischemia insults. |
| priorityDate |
2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |