| abstract |
The present invention relates to: a novel sulfonamide derivative with a fused pyrimidine skeleton, represented by chemical formula I; a solvate thereof or pharmaceutically acceptable salts thereof; and a pharmaceutical composition containing same as an active ingredient. A novel sulfonamide derivative with a fused pyrimidine skeleton, of the present invention, can effectively inhibit cancer cell growth and drug resistance, which are caused by a mutation in a tyrosine kinase domain of an epidermal growth factor receptor, or the growth of cancer cells having the resistance. |