| abstract |
Provided is a method for using a STAT3 inhibitor having a high antineoplastic effect and few side effects. An antineoplastic agent obtained by combining a quinoline carboxamide derivative represented by formula (I) (where, R1, R2, R3, R4, R5, and R6 are the same or different, and indicate a hydrogen atom, a substituted or unsubstituted aryl group, a substituted or unsubstituted aromatic heterocyclic group, COOR7 (where, R7 indicates a substituted or unsubstituted alkyl group), or OR8 (where, R8 indicates a substituted or unsubstituted alkyl group)) or a pharmaceutically acceptable salt thereof, with at least one cancer molecular targeted drug selected from an ALK inhibitor, an EGFR inhibitor, a multi-kinase inhibitor, an HER2/EGFR inhibitor, an mTOR inhibitor, a BRAF inhibitor, a MEK inhibitor, and a BCR-ABL inhibitor. |