| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a942c3402019e4bfd09e458bf77fa14 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M47-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M23-22 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-182
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-16 |
| filingDate |
2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53281afefe32b79fe3635cbc9721f429
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6f5defc6994eb70d38e27c31af3f127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7976e35ea8cedad8e6c91163197829f0 |
| publicationDate |
2020-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-2020058750-A1 |
| titleOfInvention |
A semisynthetic method of preparing neosaxitoxin |
| abstract |
A semisynthetic method of preparing neosaxitoxin in quantities of a purity sufficient to allow the compound to be used as an active pharmaceutical ingredient (API) is described. The scalable method includes the reductive desulfonation of an unresolved mixture of gonyautoxin 1 (GTX1) and gonyautoxin 4 (GTX4) isolated from an extract of a culture of Alexandrium pacificum grown to high cell densities in aerated vertical columns of amended sea water. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023118401-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-3130842-A1 |
| priorityDate |
2018-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |