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filingDate 2019-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_848ab61a707973eb84ca5a91c32ab576
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publicationDate 2020-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020057155-A1
titleOfInvention Apparatus and method for targeted ablation of cells, medium and electronic device
abstract An apparatus and method for targeted ablation of cells based on a pulsed electric field, a medium and an electronic device. The method comprises: generating a high-voltage electric pulse for targeted ablation of a target cell (S110); and applying the high-voltage electric pulse to the target cell (S120), wherein the waveform of the high-voltage electric pulse and the intensity of the electric field generated by the high-voltage electric pulse are configured according to a component structural parameter and a dielectric parameter of the target cell. A high-voltage electric pulse acting on tumor stem cells in a targeted manner to induce pyroptosis thereof can be repeatedly generated, and is applied by means of an electrode to the tumor stem cells and the high-malignancy tumor cells escaped during ablation through irreversible electroporation to induce pyroptosis thereof.
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priorityDate 2018-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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