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publicationDate 2020-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020048593-A1
titleOfInvention Network methods for neurodegenerative diseases
abstract A method of determining patient response to a neuropharmacological intervention, a method of determining a patient's likelihood of developing one or more neurological disorders, and systems for the same. The method of determining a patient's likelihood of developing one or more neurological disorders, comprising the steps of: obtaining data indicative of electrical activity within the brain of the patient; generating a network, based at least in part on the obtained data, said network comprising a plurality of nodes and directed connections between nodes,wherein the network is indicative of a flow of the electrical activity within the brain of the patient; calculating, for each node, a difference in a number and/or strength of connections into the node and a number and/or strength of connections out of the node; and determining, using the calculated differences, the patient's likelihood of developing one or more neurological disorders.
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