Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4644a074805c231782294fe337da60c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-11026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10332 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-11026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 |
filingDate |
2019-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eca8a3fe26a9b027a20e7147bb410af2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87c33418219710f09a438ced2fb18e5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf33d7fc031ec31221a709749edc61cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_681d0c816e32cb35d9ad82bf033b9b5f |
publicationDate |
2020-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020046130-A1 |
titleOfInvention |
Recombinant replication competent viruses comprising a coding region for glycogen synthase kinase-3 (gsk3) and methods of killing aberrant cells |
abstract |
The invention in one aspect relates to recombinant replication competent adenovirus that can replicate in and lyse a host cell comprising in the genome of the adenovirus a coding sequence for a glycogen synthase kinase-3 (GSK3) protein operably linked to an expression control sequence. It also relates, among others, to means and methods for treatment of cancer with a coding sequence for a glycogen synthase kinase-3 (GSK3) protein operably linked to an expression control sequence, preferably in the context of an adenovirus. This work was funded in part by European Union Horizon 2020 research and innovation programme, Marie-Sklodowska-Curie grant number 643130. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11401529-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11130968-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11077156-B2 |
priorityDate |
2018-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |