Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ef293ff0b587a62911c8850e549254a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9db15dc96772b1dd8f0cf355e02bb1ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd001b0e366c01429ef1faaa8957dd4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6cdef9d1beda8cb9baa71a812c5ea88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9ce2fc9e1a5c553fa815ac64ec46043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_545fc92c118c4653681008bf4db6de86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ab44549872ce2cec7aaed39208eb75a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b49740ab80834dc39c87b9bd38272af |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2446-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2400-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-35 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5695 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-06 |
filingDate |
2019-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0ce927f5ec003d2e0d647ea3c3ccc04c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a5cf75b82b384e39b6fc77ef56a4996 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4beafe95748d2720c968cd41b255ceaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8753b726379b050c55b8248195569101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_427d6f4686e30c897ec88e2ac0b7a67b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e4c61743801cee8457df94a97fd8801 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2820d3d9aa0cf69705d601e1553f6cb0 |
publicationDate |
2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020037160-A2 |
titleOfInvention |
Rapid diagnostics of mycobacteria with lectin conjugated particles |
abstract |
The present disclosure is generally directed to methods and systems for the rapid detection of mycobacteria in samples using lectin-conjugated silica coated magnetic nanoparticles (SMNPs). In this work, carbohydrates on the cell wall of the mycobacteria serve as binding sites for lectins conjugated on the surface of lectin-conjugated SMNPs. As the target species of mycobacteria bind to lectin-conjugated SMNPs, a precipitate forms, which can be magnetically separated from the bulk test solution to visually indicate the presence of the target species of mycobacteria. The present disclosure is utilized as an inexpensive and rapid point of care system in one embodiment. In another embodiment, the methods and systems are integrated into a lateral flow assay for rapid detection of the target species of mycobacteria. In yet another embodiment, the methods and systems are utilized to create a microfluidic detection device with increased sensitivity to mycobacteria in a sample. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022117430-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4009049-A1 |
priorityDate |
2018-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |