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filingDate 2019-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_510b88c6a3e45bc99da15da9e83162c9
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publicationDate 2020-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-2020028942-A1
titleOfInvention A super-resolution imaging method, a plurality of upconversion nanoparticle fluorophores, and a super-resolution scanning microscope
abstract Disclosed herein is a super-resolution imaging method (10). The method (10) comprises the step of, using a scanning microscope (100), scanning a sample comprising a plurality of upconversion nanoparticle fluorophores (18) with a near-infrared light beam (32) and so causing the plurality of upconversion nanoparticle fluorophores (18) to emit near-infrared fluorescence. The method comprises the step of, using the scanning microscope (100), detecting the near-infrared fluorescence emitted by each of the plurality of upconversion nanoparticle fluorophores (100), wherein the power of the near-infrared fluorescence emitted by each of the plurality of upconversion nanoparticle fluorophores (18) saturates at a power of the near-infrared light beam (32). Also disclosed herein is a plurality of upconversion nanoparticle fluorophores, a plurality of fluorophore labels, and a super-resolution scanning microscope.
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