Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_95e7278486e9ba6a3c0365c6c302909f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01017 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54 |
filingDate |
2019-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1245a3b3d49421991df17e44b4f134c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa90de73f0cae5943b4bb6344a0be872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5b0589ca59d9310633727b7750fc73e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daa16a7b17c8cab0056be7c663549404 |
publicationDate |
2020-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-2020028700-A9 |
titleOfInvention |
Tailoring site specificity of bioconjugation using step-wise atrp on proteins |
abstract |
Materials and methods for targeted and controlled addition of polymers to proteins are provided herein. For example, the methods provided herein can include contacting a protein with (i) an inactive controlled radical polymerization (CRP) initiator blocker that can reacts with amino groups on the protein but cannot serve as an initiator for polymer addition, and (ii) an active CRP initiator that reacts with amino groups on the protein and also includes a group through which a polymer can be coupled to the initiator. |
priorityDate |
2018-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |